Written by Karen Wambach
In the first of a new regular feature, The Journal of Human Lactation and Sage Publications has just launched its FIRST PODCAST entitled “On the TRAIL of cancer fighting cells in human milk: The latest research” . These podcasts will feature the author of a JHL paper in a 10-15 minute interview and will be available from the JHL website. The goal is to have at least 1 podcast per JHL issue.
In the current podcast, Editor-in-Chief Anne Merewood PhD, MPH, IBCLC, interviews Italian researchers Riccardo Davanzo MD PhD, and Giorgio Zauli MD PhD, about their paper “Human Colostrum and Breast Milk Contain High Levels of TNF-Related Apoptosis-Inducing Ligand (TRAIL)”, published online in the Journal of Human Lactation. The researchers, in a first-time effort to measure TRAIL in human milk, took samples of colostrum and mature breast milk from new mothers. Researchers then obtained samples of blood from healthy women, and various ready-to-feed infant formulas. The colostrum, mature breast milk, blood and formula were then all tested to measure their level of TRAIL. The researchers found that colostrum and breast milk contained 400- and 100-fold, respectively, higher levels of TRAIL than blood. No TRAIL was detected in the formula.
In the podcast, the authors discuss the implications of their findings with regard to the cancer prevention properties of human milk, and areas of ongoing and future research. High levels of TRAIL protein in breast milk might contribute to anticancer activity.
For subscribers to the journal, read the full study here: “Human Colostrum and Breast Milk Contain High Levels of TNF-related Apoptosis-Inducing Ligand (TRAIL)” by Riccardo Davanzo, MD, PhD; Giorgio Zauli, MD, PhD;Lorenzo Monasta, MSc, DSc; Liza Vecchi Brumatti, MSc; Maria Valentina Abate, MD;Giovanna Ventura, MD; Erika Rimondi, MSc, PhD; Paola Secchiero, MSc, PhD; and Sergio Demarini, MD. Journal of Human Lactation
Karen Wambach is the Director of Research and Special Projects for ILCA. Karen received her nursing degrees from the University of Minnesota in 1982 (BSN), and her MS (1989) and PhD in Nursing (1993) from the University of Arizona. A nurse educator, researcher, and IBCLC, Karen is Associate Professor at the University of Kansas. She has been active in ILCA at the local, regional, and international levels as a presenter, regional conference planner, and member and chair of the ILCA Research Committee. She is a member of the Missouri and Kansas Breastfeeding Coalitions and involved in evaluation of the Kansas Breastfeeding Coalition’s Business Case for Breastfeeding project. A recipient of NIH funding for a randomized clinical trial; her program of research has evolved over the years and now focuses on promotion and support of breastfeeding in vulnerable populations including adolescent mothers and ethnic minorities.